Strategic genomics uses a mix of Operations Research, Statistics, Geometric Probability, smatterings of other branches of mathematics, and Molecular Biology to craft and analyze strategies for mapping, sequencing, and analyzing DNA. Lander and Waterman wrote one of the first papers in this field in 1988. Many others have contributed since then. Many of my own papers are devoted to strategic genomics issues, many of these in collaboration with Andrew Siegel. Currently my efforts are oriented more towards the analysis of DNA sequence than on novel mapping and sequencing strategies. But, as technologies change, optimal strategies are likely to change, so there may be more great strategic genomic problems left to solve.
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